Cytokines in Trauma and Hemorrhage
Summary
Six contributions examine the release of cytokines in both experimental and clinical trauma, and hemorrhage, and discuss the experimental studies which suggest that early, prophylactic antagonists may have therapeutic efficacy in reducing morbidity and mortality in severely injured patients. Coverage includes the molecular biology of cytokines and their antagonists, bacterial translocation and its relationship to cytokine release, the experimental basis for cytokine antagonist therapy in trauma as well as in wound healing, the relationship of cytokines and antagonist therapy in lung injury, and clinical results of cytokine antagonist studies in septic patients. Distributed by Chapman & Hall. Annotation c. by Book News, Inc., Portland, Or.
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